The next Nobel prize here, spent 150 yuan back to the laboratory – Sohu Technology-musiland

The next Nobel prize here, spent 150 yuan back to the lab – Sohu of science and technology in November 2nd, Scientific Reports released a report about the application of open source hardware cytogenetics research papers, from the Rice University Tabor Lab research team. Before starting the introduction of this new tool, a brief introduction to the background of cytogenetics. In 2010, Science was chosen as the annual method of "Nature Methods", which was considered as one of the breakthrough in the past ten years. It can endure from a simple experiment shows: through the application of light genetics, researchers need to light the lamp on the head of rats, the rats will immediately begin to turn around. Turn off the lights and then stop. Dynamic video cut from Nature Methods popular, the experimental mice by finding out driving around neurons in these cells, and then covered with light sensitive to specific protein. By lighting the light, the light-sensitive proteins are stimulated to activate the neurons and direct the mouse to turn. Cytogenetics has two major functions: 1 for intracellular target protein tracking; specific neural activity 2 selectively control certain cells in the brain (as above). And drugs and electrode stimulation, compared with the light of the superior accuracy of the researchers get deep. Figure Karl Gerhardt (left) in the application of LPA in the light of genetic experiments in the cultivation of cells in the past 5-10 years, basically all biological engineering research to be used in light genetics. But the problem is that in neuroscience, we expand in optogenetic way, it is to do research on the biological tools, such as photosensitive protein, gene expression system, protein interaction and so on, no one can research more convenient to use these biological tools hardware. Karl Gerhardt said that he is the introduction of the optical genetics open source hardware tools Light Plate Apparatus (LPA), one of the major R & D personnel. LPA is the most simple and low-cost tool for genetic manipulation. LPA = each researcher can use on genetic technology over the years, many biologists have come to us and say they want to apply optogenetics to their study, but they do not know where to start to build the required optical instrument. We believe that the arrival of LPA will mean that almost any biological laboratory can easily apply the optical genetic technology to the experiment. Jeff Tabor said he was the main staff of the study, Karl Gerhardt teacher. Pictured Karl Gerhardt (left) holding LPA and Jeff Tabor (right) photo Tabor Lab in order to pass L Bo相关的主题文章: